Mu nganda zimiti nintungamubiri, capsules yubusa ikora ibiyobyabwenge byingenzi, kandi guhagarara kwayo bigira ingaruka kumutekano no mumikorere yimiti. Abakozi benshi bashinzwe gutanga amasoko n'abashinzwe gutanga umusaruro bakunze kubaza bati: "Ubushuhe bwo kubika ni ubuhe busa?" Iki nikibazo gikomeye, nkuko capsule shell ifite hygroscopicity ikomeye kandi ikumva ibidukikije. Ukurikije Pharmacopoeia yo mu Bushinwa hamwe n’inganda rusange z’inganda, ubuhehere bugereranije bwo kubika capsules yubusa bugomba kugenzurwa cyane hagati ya 35% na 65%.
Kuki kugenzura ubuhehere ari ngombwa?
Ikintu cyibanze cya capsules yubusa ni gelatine, ibikoresho bya hydrophilique polymer. Ubushuhe bwihariye (35% -65%) bwashyizweho bushingiye kumiterere yumubiri wa capsules ubwabo. Ku rwego rwuruganda, ubushuhe bwa capsules busanzwe bugenzurwa hagati ya 12.5% na 17.5%, aribwo buryo bwiza bwo gukomeza imbaraga za mashini no gukomera.
Niba ubuhehere bwibidukikije buri hejuru ya 65%, capsules izahita ikuramo ubuhehere buturuka mu kirere, bigatuma ubuhehere burenga urugero. Ingaruka zigaragara nko koroshya no gukomera kwa capsule igaragara. Mu bihe bikomeye, biganisha ku gufatira umubiri wa capsule na cap, kurinda gutandukana neza kumashini zuzuza byikora, bityo bigatuma umusaruro uhagarara cyangwa kwiyongera kwangwa. Byongeye kandi, ibidukikije - ibidukikije bikunda gukura mikorobe, biganisha kuri capsule.
Ku rundi ruhande, niba ubuhehere bwibidukikije buri munsi ya 35%, ubuhehere buri muri capsules buzimukira mu kirere, bigatuma ibishishwa bya capsule bitakaza ubushuhe kandi bikavunika. Muri iyi leta, capsules ikunda kumeneka cyangwa kuryama mugihe cyo gutwara cyangwa kuzuza ibintu, bigira ingaruka kumiterere yibicuruzwa kandi bishobora gutera ifu kumeneka.
Nigute ushobora gucunga ubumenyi mubidukikije?
Ntabwo bihagije kumenya gusa ububiko bwububiko bwa capsules yubusa; urufunguzo ruri mubikorwa. Hano hari ibitekerezo byinshi bifatika:
Guhuza Ubushyuhe hamwe nubushuhe: Ubushuhe nubushuhe akenshi bigira ingaruka kuri mugenzi we. Ubushyuhe busanzwe bwububiko bwa capsules busanzwe burasabwa kuba hagati ya dogere 10 na dogere 25. Ubushyuhe bwinshi nubushuhe bwinshi ni kirazira mububiko bwa capsule, kwihuta gusaza kwa gelatine no guhindura ibintu. Ububiko bugomba kuba bufite ibikoresho byo kugenzura ubushyuhe nubushuhe, hamwe nibisanzwe bibikwa.
Akamaro ko gupakira bifunze: Kuri capsules idafunguwe, ubusugire bwibipfunyika byumwimerere bigomba kubungabungwa kugirango birinde guhumeka neza. Kuri capsules yafunguwe ariko idakoreshwa, igomba kuba re - ifunze kandi igakoreshwa vuba bishoboka. Birasabwa gushyira desiccants ikwiye mumasanduku yo gupakira niba ibintu byemewe.
Gutondekanya bisanzwe: Ibikoresho byabitswe bigomba gushyirwa ku gipangu, ukurikije ubutaka butagaragara -, hanze - uburyo bwo gucunga urukuta. Ibi bituma umwuka uhumeka neza mububiko kandi bikarinda ubuhehere buke bwaho bigatuma udusanduku duhinduka.
Muri make, ubushuhe busanzwe bwo kubika kuri capsules yubusa nubushuhe bugereranije bwa 35% -65%, hamwe nubushyuhe bwa dogere 10 -25. Kugenzura ubushyuhe bukabije nubushuhe ntibisabwa gusa kubahiriza amabwiriza ya GMP ahubwo ni ingamba zifatika zo gukora neza no kugabanya igihombo cyibigo. Ku masosiyete akora ibya farumasi, gushyiraho uburyo bunoze bwo kugenzura ibidukikije mu bubiko ni urufunguzo rwo kurinda igenzura rya mbere ry’ubuziranenge bwa capsule. Niba hari ibisabwa kuri capsules yubusa, ikaze kuvugana na KornnacCaps.
